Biofilm formation
Bacteria form and maintain biofilm through the process of quorum sensing.
Biofilm eradication
AHV’s proprietary technology disrupts the quorum sensing process and eradicates biofilm structure.
Clearing
Without the “protection” of biofilm, pathogenic bacteria become susceptible to immune cells, reduces the need for antibiotics.
Figure 1: Our Fundamental lab research, our basis for our product development
AHV FUNDAMENTAL RESEARCH: BIOFILM ERADICATION STUDIES
Our team of microbiologists is able to cultivate a wide range of bacterial biofilm in AHV’s BSL-2 laboratory. Via these bacterial biofilms, AHV is able to select the plant molecules that are able to avoid biofilm formation (MBIC) or to eradicate existing biofilms (MBEC).
This research has led to our patend pending innovative anti-biofilm compounds, or QQs extracted from natural resources. With our wide range of innovations and solutions for animal health, AHV supports and empowers the farming community through new standards for animal health management and care.
In multiple independent studies, mature biofilms (figure 2: Control dosage) were examined using different dosages (figure 3: High dosage) of the AHV QSA Technology active anti biofilm compounds.
Figure 2: Untreated bacterial biofilm (AHV International, 2021)
Figure 3: Biofilm eradication with AHV QSA Technology active compounds (AHV International, 2021)
Bacterial biofilm visualized from the top in a Nikon confocal laser scanning microscope. Green signals represent the living bacteria, red signals represent dead bacteria. The top panel resembles the control with untreated biofilm. The bottom panel shows biofilm treated with active AHV QSA Technology compounds. The results of the core AHV QSA Technology were measured after one day (figure 3). A clear reduction / breakdown of the biofilm was already established because of a high amount of dead bacteria and a few living bacteria.
FROM RESEARCH TO PRODUCTS
Our AHV QSA Technology inhibits bacterial communication, avoids biofilm formation and reduces virulency. Our products promote the (natural) immune system of the body cells and support the animals’ energy and mineral metabolism.
Product strategy
Based on mode of action
Figure 4: AHV Product Strategy (AHV International, 2021)